Terminator sequence definition8/17/2023 ![]() ![]() "Transcription termination at intrinsic terminators: the role of the RNA hairpin". ↑ Wilson KS, von Hippel PH (September 1995).Sudbury, MA: Jones and Bartlett Publishers. This should not be confused with terminator codons that are the stopping signal for translation. readthrough The continuation of transcription of DNA beyond a normal stop signal, or terminator sequence, due to failure of RNA polymerase to recognize the. Science Biology Genetics chapter fifteen: genes and how they work 5.0 (1 review) Consider the pathway for synthesis of arginine from glutamate by Neurospora crassa as shown on the diagram. Erpin (Gautheret & Lambert, 2001) is given a structure-annotated alignment of 1200 terminator sequences from Bacillus subtilis and Escherichia coli as a training set. The search procedure uses two complementary programs, Erpin and RNAmotif. The temporary lapse and weak uracil-adenine bonds cause the hairpin structure to unwind and dissociate from the RNA polymerase, thus terminating transcription. terminator sequence Definition: Search for: Biology Glossary search by AKA: terminator, Rho-independent termination site A sequence in DNA that signals termination of transcription to RNA polymerase. Change Principles ARNold finds rho-independent terminators in nucleic acid sequences. The transcription of the uracil sequence is coupled with a protein, located on the RNA polymerase, binding to the hairpin structure causing the RNA polymerase to temporarily stop. The terminators of the present invention are especially optimized for the T7 RNA. The mRNA molecule has a sequence of base pairs with a high proportion of cytosine and guanine bases, these are able to strongly bond to one another with 3 hydrogen bonds forming a RNA duplex in a stable hairpin structure succeeding the hairpin structure is a chain of uracil bases, which only form weak bonds with adenine. Terminators are sequences that hinder or stop transcription of a polymerase. Rho-independent termination (also known as intrinsic termination) is a process carried out in prokaryotic organisms as a mechanism for stopping transcription. Translation: The big picture Translation involves decoding a messenger RNA (mRNA) and using its information to build a polypeptide, or chain of amino acids. ![]()
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